Antibody response to Equine Herpesvirus-1 in mares with a history of abortion in municipalities of Meta, Colombia
DOI:
https://doi.org/10.22579/20112629.813Keywords:
Virus latency, trigeminal ganglion, Meningoencephalitis, epidemiology, EquineAbstract
Equine herpesvirus type 1 (EHV-1) is a widespread virus responsible for significant economic losses in the equine industry. In Colombia, there is limited knowledge about this virus, making it necessary to understand its epidemiological behavior in detail. The objective of this study was to evaluate the association between the serological response to EHV-1 and the occurrence of abortion in mares from six municipalities in the Meta department. A case-control design was used with 76 mares (N=37 cases and N=39 controls). The diagnostic test was a commercial indirect ELISA kit. Frequency analysis was performed using the chi-square test of independence, and associated factors were analyzed using odds ratios (OR). Abortion was not associated with the serological response (OR=0.70). However, 58.3% of overweight mares experienced abortion, indicating that overweight status was a significant associated factor. In mares used for sport, the abortion rate was higher (53.8%) than in those used for fieldwork (11.5%) (p < 0.05). Overall seropositivity was 48.7%, with the following rates by municipality: Restrepo 62.5% (5/8), Puerto López 62.5% (5/8), Acacias 55.6% (5/9), Cumaral 54.5% (12/22), Villavicencio 45.5% (5/11), and Barranca de Upía 27.8% (5/18). Abortion was not associated with the presence of antibodies to EHV-1, suggesting other causes that may explain this clinical picture. The virus is widely distributed across the municipalities of Meta, suggesting an endemic presence and highlighting the need for effective prevention and control strategies.
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